Usage and Purpose of Eltrombopag

Randomized trials are at the top of the hierarchy of epidemiological study design because they provide the most powerful evidence of a possible causal association between exposure (or treatment) and outcome.

To prepare- Review the provided trials and intention to treat.

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Usage and Purpose of Eltrombopag
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To complete this Application Assignment:

• Write a 2-page paper (APA style) in which you propose a randomized trial to investigate an association of interest.
• It can be the same association you identified last week or a different one entirely.
• In addition to the study features you covered in last week’s assignment, elaborate on the specific advantages of randomization in your planned trial.
• Describe how “intention to treat” might affect the design and analysis of the experiment.

Article: Mark, K., Meinzen-Derr, J., Stephenson, R., Haworth, A., Ahmed, Y., Duncan, D., & … Allen, S. (2007). Contraception among HIV concordant and discordant couples in Zambia: a randomized controlled trial. Journal Of Women’s Health (15409996), 16(8), 1200-1210. doi:10.1089/jwh.2006.0238

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